Effects of Coccinia indica and tolbutamide on human bloodsuger values

Pritsana Khamchaew, Edwin ten Winkel, bbPharma

Abstract. Coccinia indica (Climbing ivy gourd) is a herb used in traditional and Ayurvedic medicine in India where it is often combined with Abroma augusta.

100 patients with confirmed type II Diabetes mellitus were rondomized over two groups. One group received 2dd 200mg/kg of Coccinia indica (in watery extract, freeze dried and encapsulated), wheras the other group recieved Tolbutamide 2dd 200mg/kg. Treatment results were determined after 45 days.

Both Coccinia Indica and Tolbutamide caused a statistical and clinically significant lowering of bloodsuger values in comparison to base values. There were no statistically significant differences between patients treated with Coccinia Indica and patients treated with tolbutamide.