The effect of BBP162, a new selective serotonin reuptake inhibitor, on reproductive behaviour on snails was tested on the snail Biomphalaria straminae.
Snails were placed in solutions of BBP162 of ascending strength (2, 5 and 10 μM).
All snails showed praeputium eversion within 10 hours and developed erections. After 72 hours erections started to fade.
MED ≤ 2μM as all snails on the lowest dose showed significant effect.
Ref.:- G. Nentwig: Another Example of Effects of Pharmaceuticals on Aquatic Invertebrates: Fluoxetine and Ciprofloxacin. In: Pharmaceuticals in the Environment (Ed: Klaus Kümmerer): Pub: Springer Berlin Heidelberg, 2008, Ch. 13
- Fong, Olex, Farrell, Majcharzak, Muschamp: Induction of preputium eversion by peptides, serotonin receptor antagonists, and selective serotonin reuptake inhibitors in Biomphalaria glabrata. Invertebrate Biology. V124, 4. P296-302
- Gust, Buronfosse, Giamberini, Ramil, Mons and Garric: Effects of fluoxetine on the reproduction of two prosobranch mollusks: Potamopyrgus antipodarum and Valvata piscinalis. Environmental Pollution Volume 157, Issue 2, February 2009, Pages 423-429
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